03.04 Journal Articles
Peer-reviewed journal articles by LUSH.AI founder Prof. Alex Stokes — highlights first, then the full record in reverse-chronological order.
Highlights
Systemic biases are leading to an intersex research void
2024Nature
Nature piece — on how systemic biases have created a research void in intersex health — and what to do about it.
Implementation of a computational medical assemblage heuristic to improve rational design of phytomedicines for safety, efficacy and regulatory approval
2026Frontiers in Pharmacology
A computational framework that operationalises the Chief–Deputy–Assistant–Envoy (CDAE) heuristic from Asian medicine to rationally simplify multi-species phytomedicine formulations — bridging traditional formulation logic with pharmacological informatics.
All journal articles — reverse-chronological
Evidence and tradition in dialogue: biological sex variability in phytomedicine research as a foundation for safety, efficacy, and robust evidence standards DOI ↗Medicines · 2026
Developing STEMM systems navigator roles informed by social-ecological and Hawaiʻi–Pacific wayfinding models DOI ↗Pacific Dynamics · 2025
A pathway to next-generation mast cell stabilizers identified through the novel Phytomedical Analytics for Research Optimization at Scale (PAROS) data platform DOI ↗bioRxiv · 2025
Computational analysis of therapeutic potential for simplified Piper spp.-derived medicinal mixtures in anxiety, sleep, pain and seizure DOI ↗bioRxiv · 2025
Bayesian analysis of ahi consumption and methylmercury levels in the blood: a course-based research experience in an undergraduate data science majorSSRN / Elsevier · 2025
Development and implementation of a multimodal data-science upskilling program for military-affiliated students in the Hawaiʻi–Pacific regionSSRN / Elsevier · 2025
Building a cybertraining program for climate scientists in the Pacific to integrate cyberinfrastructure and open sciencePractice and Experience in Advanced Research Computing (PEARC) · 2024
Identification of minimum essential therapeutic mixtures from cannabis plant extracts by screening in cell and animal models of Parkinson's diseaseFrontiers in Pharmacology · 2022
Medicine in motion: data analytics-based solutions for traditional medicine integration into Western medical practiceJournal of Ethnopharmacology · 2021
O2-dependent protein internalization underlies astrocytic sensing of acute hypoxia by restricting multimodal TRPA1 channel responsesCurrent Biology · 2020
Cannabis chemovar nomenclature misrepresents chemical and genetic diversityCannabis and Cannabinoid Research · 2020
TRPV1 is a component of the atrial natriuretic signaling complex and a valid therapeutic target in cardiac hypertrophy and heart failureChannels · 2019
Diverse TRPV1 responses to cannabinoidsChannels · 2019
Myrcene and terpene regulation of TRPV1Channels · 2019
Calcium-dependent, non-apoptotic large plasma membrane bleb formation in physiologically stimulated mast cells and basophilsJournal of Extracellular Vesicles · 2019
Insulin-induced lipid body accumulation is accompanied by lipid remodelling in model mast cellsAdipocyte · 2019
Cannabinoids, the heart of the matterJournal of the American Heart Association · 2018
Cannabinoid therapeutics in Parkinson's disease: promise and paradoxJournal of Herbs, Spices & Medicinal Plants · 2017
Comparative genomics explains the evolutionary success of reef-forming coralseLife · 2016
Prevalence of antibodies to Zika virus in mothers from Hawaii who delivered babies with and without microcephaly, 2009–2012PLoS Neglected Tropical Diseases · 2016
Fluorescence imaging of posterior spiracles from forensically important Chrysomya rufifaciesJournal of Forensic Sciences · 2016
Differential regulation of calcium signalling pathways by components of Piper methysticum ('awa)Phytotherapy Research · 2015
The calcium release-activated calcium channel Orai1 in hypertrophic compensation and dilated cardiomyopathyChannels · 2014
The transmembrane channel-like protein family and human papillomavirusesOncoimmunology · 2014
Lipid body accumulation alters calcium signaling dynamics in immune cellsCell Calcium · 2014
Successful TRPV1 antagonist treatment for cardiac hypertrophy and heart failure in miceChannels · 2013
Pacific island 'awa (kava) extracts, but not isolated kavalactones, promote proinflammatory responses in model mast cellsPhytotherapy Research · 2012
Mice lacking functional TRPV1 are protected from pressure-overload cardiac hypertrophyChannels · 2011
Regulation of cardiac hypertrophy by the calcium channel TRPV1American Heart Association · 2010
Secretogranin III directs secretory vesicle biogenesis in mast cells via interaction with chromogranin AJournal of Immunology · 2008
TRPM4 controls insulin secretion in pancreatic β-cellsCell Calcium · 2007
Link between TRPV channels and mast cell functionTRP Channels (Handbook) · 2007
TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLDCellular Signalling · 2006
FcεRI control of Ras via inositol (1,4,5) trisphosphate 3-kinase and inositol tetrakisphosphateCellular Signalling · 2006
Formation of a physiological complex between TRPV2 and RGA protein promotes cell-surface expression of TRPV2Journal of Cellular Biochemistry · 2005
A TRPV2–PKA signaling module for transduction of physical stimuli in mast cellsJournal of Experimental Medicine · 2004
RGA protein associates with a TRPV ion channel during biosynthesis and traffickingJournal of Cellular Biochemistry · 2004
Differential roles of CB1 and CB2 cannabinoid receptors in mast cellsThe Journal of Immunology · 2003
Demographic and clinical characteristics of adolescents in Hawaii with obsessive-compulsive disorderArchives of Pediatrics & Adolescent Medicine · 2003
LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viabilityNature · 2001
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homologyNature · 2001
The expression of receptor tyrosine phosphatases is responsive to sciatic nerve crushMolecular and Cellular Neuroscience · 1998
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